The last step needs only three parameters related to the
addition of noise to expression data. In fact, the procedure consider
two types of noise: the first one affects the classification of the
tissues and is characterized by the parameter
, which represents
the probability that a wrong label is assigned. The second one is
noise added to gene expression data obtained from the second step. In
this case, with a fixed probability
, a real value, chosen
according to a normal distribution with mean 0 and standard deviation
, is added to each element of the matrix. It
follows that values for the parameters
,
and
must be
selected to perform the final step of the procedure.